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(ADOS®-2) Autism Diagnostic Observation Schedule™, Second Edition

by Catherine Lord, PhD, Michael Rutter, MD, et al.
Expedited Shipping
Yes
Translation
Available in Czech, Danish, Dutch, Finnish, French, German, Italian, Norwegian, & Swedish
Published Translations
Format
Standardized behavior observation and coding
ADMIN TIME
40–60 minutes
Ages
12 months through adulthood
Benefit
Allows you to accurately assess and diagnose autism spectrum disorders across age, developmental level, and language skills
Publish Date
2012
Qualifications
Level C required.

About Qualification Levels

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(ADOS®-2) Autism Diagnostic Observation Schedule, Second Edition

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Kits & Manuals
ADOS-2 Hand-scored Kit
SKU: W-605

Includes ADOS-2 Manual; 50 Protocol Booklets (10 per Module); Test Materials (100+ stimulus items); all in a durable plastic container with handles and wheels. Please Note: ADOS-2 Kits shipped to Alaska, Hawaii, or internationally are subject to increased shipping rates. A customer service representative will confirm all charges with customers prior to processing orders including kits.

1 x ADOS-2 Hand-scored Kit   + $2,595.00
Kits & Manuals
ADOS-2 Hand-scored Upgrade Package
SKU: W-606

Includes ADOS-2 Manual; 50 Protocol Booklets (10 for each Module); Additional Toddler Module Stimulus Items (15 items that when added to your existing ADOS Kit allow for Toddler Module administration).

1 x ADOS-2 Hand-scored Upgrade Package   + $799.00
Kits & Manuals
ADOS-2 Software Kit
SKU: W-605S

Includes ADOS-2 Manual; 50 Protocol Booklets (10 per Module); Test Materials (100+ stimulus items); plus Unlimited-Use Computer Scoring CD (W-605U); all in a durable plastic container with handles and wheels. Requires PC with Windows 10, 8, 7, Vista or XP. CD-ROM drive and USB port required. Please Note: ADOS-2 Kits shipped to Alaska, Hawaii, or internationally are subject to increased shipping rates. A customer service representative will confirm all charges with customers prior to processing orders including kits.

1 x ADOS-2 Software Kit   + $2,695.00
Kits & Manuals
ADOS-2 Software Upgrade Package
SKU: W-606S

Includes ADOS-2 Manual; 50 Protocol Booklets (10 for each Module); Additional Toddler Module Stimulus Items (15 items that when added to your existing ADOS Kit allow for Toddler Module administration); Unlimited-Use Scoring CD (W-605U). Requires PC with Windows 10, 8, 7, Vista or XP. CD-ROM drive and USB port required. 

1 x ADOS-2 Software Upgrade Package   + $975.00
Forms
ADOS-2 Spanish Language Protocol Booklet: Module 1 (Pack of 10)
SKU: TEA-10B
1 x ADOS-2 Spanish Language Protocol Booklet: Module 1 (Pack of 10)   + $83.00
Forms
ADOS-2 Spanish Language Protocol Booklet: Module 2 (Pack of 10)
SKU: TEA-10C
1 x ADOS-2 Spanish Language Protocol Booklet: Module 2 (Pack of 10)   + $83.00
Forms
ADOS-2 Spanish Language Protocol Booklet: Module 3 (Pack of 10)
SKU: TEA-10D
1 x ADOS-2 Spanish Language Protocol Booklet: Module 3 (Pack of 10)   + $83.00
Forms
ADOS-2 Spanish Language Protocol Booklet: Module 4 (Pack of 10)
SKU: TEA-10E
1 x ADOS-2 Spanish Language Protocol Booklet: Module 4 (Pack of 10)   + $83.00
Forms
ADOS-2 Protocol Booklet Toddler Module (Pack of 10)
SKU: W-605A
1 x ADOS-2 Protocol Booklet Toddler Module (Pack of 10)   + $83.00
Forms
ADOS-2 Protocol Booklet Module 1 (Pack of 10)
SKU: W-605B
1 x ADOS-2 Protocol Booklet Module 1 (Pack of 10)   + $83.00
Forms
ADOS-2 Protocol Booklet Module 2 (Pack of 10)
SKU: W-605C
1 x ADOS-2 Protocol Booklet Module 2 (Pack of 10)   + $83.00
Forms
ADOS-2 Protocol Booklet Module 3 (Pack of 10)
SKU: W-605D
1 x ADOS-2 Protocol Booklet Module 3 (Pack of 10)   + $83.00
Forms
ADOS-2 Protocol Booklet Module 4 (Pack of 10)
SKU: W-605E
1 x ADOS-2 Protocol Booklet Module 4 (Pack of 10)   + $83.00
Forms
ADOS-2 Spanish Language Protocol Booklet: Toddler Module (Pack of 10)
SKU: TEA-10A
1 x ADOS-2 Spanish Language Protocol Booklet: Toddler Module (Pack of 10)   + $83.00
ADOS-2 Spanish Language Add-On Set
SKU: TEA-10
Includes 50 Protocol Booklets (10 for each Module); Manual; 2 Storybooks; 1 Pop-Up Toy; all in Spanish. Note: You must purchase an English language ADOS-2 Kit (W-605 or W-605S) to obtain the Test Materials required for administration.
1 x ADOS-2 Spanish Language Add-On Set   + $799.00
Kits & Manuals
ADOS-2 Training DVD Guidebook and Protocols CD
SKU: W-605CV
For use with the ADOS-2 DVD Training Resources Package and the ADOS-2 DVD Training Resources Upgrade Package. Includes CD with printable PDFs of all Training Resources Protocol Booklets.
1 x ADOS-2 Training DVD Guidebook and Protocols CD   + $152.00
Kits & Manuals
ADOS-2 Software Kit
SKU: W-605S

Includes ADOS-2 Manual; 50 Protocol Booklets (10 per Module); Test Materials (100+ stimulus items); plus Unlimited-Use Computer Scoring CD (W-605U); all in a durable plastic container with handles and wheels. Requires PC with Windows 10, 8, 7, Vista or XP. CD-ROM drive and USB port required. Please Note: ADOS-2 Kits shipped to Alaska, Hawaii, or internationally are subject to increased shipping rates. A customer service representative will confirm all charges with customers prior to processing orders including kits.

1 x ADOS-2 Software Kit   + $2,695.00
Kits & Manuals
ADOS-2 Software Upgrade Package
SKU: W-606S

Includes ADOS-2 Manual; 50 Protocol Booklets (10 for each Module); Additional Toddler Module Stimulus Items (15 items that when added to your existing ADOS Kit allow for Toddler Module administration); Unlimited-Use Scoring CD (W-605U). Requires PC with Windows 10, 8, 7, Vista or XP. CD-ROM drive and USB port required. 

1 x ADOS-2 Software Upgrade Package   + $975.00
ADOS-2 Unlimited-Use Scoring CD
SKU: W-605CD
1 x ADOS-2 Unlimited-Use Scoring CD   + $401.00
Kits & Manuals
ADOS-2 Software Kit
SKU: W-605S

Includes ADOS-2 Manual; 50 Protocol Booklets (10 per Module); Test Materials (100+ stimulus items); plus Unlimited-Use Computer Scoring CD (W-605U); all in a durable plastic container with handles and wheels. Requires PC with Windows 10, 8, 7, Vista or XP. CD-ROM drive and USB port required. Please Note: ADOS-2 Kits shipped to Alaska, Hawaii, or internationally are subject to increased shipping rates. A customer service representative will confirm all charges with customers prior to processing orders including kits.

1 x ADOS-2 Software Kit   + $2,695.00
Kits & Manuals
ADOS-2 Software Upgrade Package
SKU: W-606S

Includes ADOS-2 Manual; 50 Protocol Booklets (10 for each Module); Additional Toddler Module Stimulus Items (15 items that when added to your existing ADOS Kit allow for Toddler Module administration); Unlimited-Use Scoring CD (W-605U). Requires PC with Windows 10, 8, 7, Vista or XP. CD-ROM drive and USB port required. 

1 x ADOS-2 Software Upgrade Package   + $975.00
Kits & Manuals
ADOS-2 Manual
SKU: W-605M
1 x ADOS-2 Manual   + $160.00
Kits & Manuals
ADOS-2 Spanish Language Manual
SKU: TEA-10M
1 x ADOS-2 Spanish Language Manual   + $160.00
Kits & Manuals
ADOS-2 Online Manual
SKU: W-605MP
1 x ADOS-2 Online Manual   + $136.00
Training and CE
ADOS-2 Training Video Program
SKU: LMS-605

Online self-study for learning all five modules of the ADOS-2. Includes online videos and associated digital support materials on the WPS Learning Management System (WPS LMS). (For CE credit, see Independent Study: ADOS-2 Training Video Program [LMS-605CE].)

1 x ADOS-2 Training Video Program   + $1,277.00
Training and CE
Independent Study: ADOS-2 Training Video Program
SKU: LMS-605CE

Includes post-test materials available online on the WPS Learning Management System (WPS LMS). Purchase these post-test materials and complete them on the WPS LMS to receive 30 continuing education (CE) credits for mastering the content of the ADOS-2 Training Video Program (sold separately, LMS-605 on the WPS LMS or W-605DVD in DVD format). These post-test materials cover the five-module video training.

1 x Independent Study: ADOS-2 Training Video Program   + $450.00
Training and CE
Independent Study: ADOS-2 Manual
SKU: LMS-605MCE

Includes post-test materials available online on the WPS Learning Management System (WPS LMS). Purchase these post-test materials and complete them on the WPS LMS to receive 6 continuing education (CE) credits for mastering the content of the ADOS-2 Manual (sold separately, W-605M in print format or W-605MP in online format on the WPS Online Evaluation System).

1 x Independent Study: ADOS-2 Manual   + $90.00
Training and CE
ADOS-2 Training Video Program Upgrade
SKU: LMS-606

Online self-study for learning the Toddler Module of the ADOS-2. For use with the original ADOS DVD Training Package, or for individuals already trained on ADOS Modules 1 through 4 (via live clinical workshops or the ADOS DVD Training Package). Includes online videos and associated digital support materials on the WPS Learning Management System (WPS LMS). (For CE credit, see Independent Study: ADOS-2 Video Training - Toddler Module [LMS-606CE].)

1 x ADOS-2 Training Video Program Upgrade   + $403.00
Training and CE
Independent Study: ADOS-2 Video Training - Toddler Module
SKU: LMS-606CE

Includes post-test materials available online on the WPS Learning Management System (WPS LMS). Purchase these post-test materials and complete them on the WPS LMS to receive 12 continuing education (CE) credits for mastering the content of the ADOS-2 Training Video Program Upgrade (sold separately, LMS-606 on the WPS LMS or W-606DVD in DVD format). These post-test materials cover Toddler training only and can also be used with the Toddler training materials provided in the ADOS-2 Clinical Workshop materials.

1 x Independent Study: ADOS-2 Video Training - Toddler Module   + $180.00
Training and CE
Los Angeles, CA (March 20 – 21, 2023)
SKU: LMS-607_LE_B_23

Los Angeles, CA (March 20 – 21, 2023)

1 x Los Angeles, CA (March 20 – 21, 2023)   + $550.00
Training and CE
April Webinar (April 13 – 14, 2023)
SKU: LMS-607_LW_B_23

April Webinar (April 13 – 14, 2023)

1 x April Webinar (April 13 – 14, 2023)   + $550.00
Training and CE
Philadelphia, PA (May 8 – 9, 2023)
SKU: LMS-607_LE_C_23

Philadelphia, PA (May 8 – 9, 2023)

1 x Philadelphia, PA (May 8 – 9, 2023)   + $550.00
Kits & Manuals
ADOS-2 Online Manual
SKU: W-605MP
1 x ADOS-2 Online Manual   + $136.00

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(ADOS™-2) Autism Diagnostic Observation Schedule™, Second Edition
(ADOS®-2) Autism Diagnostic Observation Schedule™, Second Edition

In stock

$67.00

Summary

    About This Product

    Safety Warning: CHOKING HAZARD - Small parts. Not for children under 3 years. 

    For any questions you may have that were not answered in the below description, please click here for additional FAQs regarding the ADOS-2.

    Modules 1 through 4 by Catherine Lord, PH.D., Michael Rutter, MD, FRS, Pamela C. Dilavore, PH.D., Susan Risi, PH.D., Katherine Gotham, PH.D., and Somer L. Bishop, PHD

    Toddler Module by Catherine Lord, PH.D., Rhiannon J. Luyster, PH.D., Katherine Gotham, PH.D., and Whitney Guthrie, M.S.

    From the World's Leading Autism Experts

    This revision improves an instrument already viewed as the “gold standard” for the observational assessment of autism spectrum disorders (ASDs). With updated protocols, revised algorithms, a new Comparison Score, and a Toddler Module, the ADOS-2 provides a highly accurate picture of current symptoms, unaffected by language. It can be used to evaluate almost anyone suspected of having ASD—from 1-year-olds with no speech to adults who are verbally fluent.

    Like its predecessor, the ADOS-2 is a semistructured, standardized assessment of communication, social interaction, play, and restricted and repetitive behaviors. By observing and coding these behaviors, you can obtain information that informs diagnosis, intervention, treatment planning, and educational placement.

    Five Modules

    The ADOS-2 includes five modules, each requiring just 40 to 60 minutes to administer. The individual being evaluated is given only one module, selected based on his or her expressive language level and chronological age.

    • Toddler Module—for children between 12 and 30 months of age who do not consistently use phrase speech
    • Module 1—for children 31 months and older who do not consistently use phrase speech
    • Module 2—for children of any age who use phrase speech but are not verbally fluent
    • Module 3—for verbally fluent children and young adolescents
    • Module 4—for verbally fluent older adolescents and adults

    Each module engages the examinee in a series of activities involving interactive stimulus materials (all included in the ADOS-2 Kit). To illustrate, activities in Module 3 are listed below:

    • Construction Task
    • Make-Believe Play
    • Joint Interactive Play
    • Demonstration Task
    • Description of a Picture
    • Telling a Story From a Book
    • Cartoons
    • Conversation and Reporting
    • Emotions
    • Social Difficulties and Annoyance
    • Break
    • Friends, Relationships, and Marriage
    • Loneliness
    • Creating a Story

    Standardized Administration, Coding, and Scoring

    Each ADOS-2 module has its own Protocol Booklet, which structures the administration and guides you through coding and scoring. As you administer activities, you observe the examinee and take notes. Immediately afterward, you code the behaviors observed. Then you use the algorithm form for scoring.

    In Modules 1 through 4, algorithm scores are compared with cutoff scores to yield one of three classifications: autism, autism spectrum, or non-spectrum. The difference between autism and autism spectrum classifications is one of severity, with the former indicating more pronounced symptoms. In the Toddler Module, algorithms yield “ranges of concern” rather than classification scores.  

    Improved Protocol Booklets, Revised Algorithms, and a New Comparison Score

    Administration and coding procedures for the ADOS-2 are functionally identical to those for the ADOS. Modules 1 through 4 retain the same basic activities and codes, though some have been expanded and several new codes have been added. Protocol Booklets for these modules have been significantly improved—now providing clearer, more explicit administration and coding instructions.

    Algorithms for Modules 1 through 3 have been revised to achieve more accurate and useful results and to provide a more uniform basis for comparing results across the three modules used with children and young adolescents. 

    A new Comparison Score for Modules 1 through 3 allows you to look at a child’s overall level of autism spectrum–related symptoms against children diagnosed with ASD who are the same age and have similar language skills. This score also makes it easier to monitor an individual’s symptoms over time.

    The New Toddler Module

    The Toddler Module is designed specifically for children between 12 and 30 months of age who do not consistently use phrase speech. Observations are coded immediately following administration, and the codes are converted to algorithm scores. Toddler Module algorithms provide “ranges of concern” rather than cutoff scores. These ranges help you form clinical impressions, but they avoid formal classification—which may not be appropriate at such a young age. The Toddler Module quantifies risk for ASD and guides further monitoring.

    The Most Accurate Picture of Current ASD Symptoms

    With improved algorithms, the ADOS-2 demonstrates strong predictive validity. It gives you a highly accurate picture of current ASD-related symptoms, based on real-time observations. Physicians, clinical psychologists, school psychologists, speech–language pathologists, and occupational therapists can use ADOS-2 results to inform diagnosis, intervention, educational placement, and treatment planning. Because it can be used with a wide range of children and adults, the ADOS-2 is an essential addition to any hospital, clinic, or school that serves individuals with developmental disorders.

    Training Options

    ADOS-2 administration and coding are highly standardized. Therefore, valid assessment requires training. A variety of training options are available (all offer opportunities to earn continuing education credits):

    ADOS-2 Clinical Workshops

    • Live in-person training and live webinars. These 2-day workshops provide instructor-led introductory training on the ADOS-2.
    • Designed for professionals using the ADOS-2 in clinical practice or research (completion of a Clinical Workshop satisfies the prerequisite requirement for attending advanced research workshops offered through the authors and their colleagues.)
    • For information about these training options, visit the ADOS-2 Workshop page.

    ADOS-2 Training Video Program and Upgrade

    • Online self-study for learning the ADOS-2
    • Designed for professionals using the ADOS-2 in clinical practice (those who plan to use the ADOS-2 in research need to attend live clinical and research workshops)
    • The ADOS-2 Training Video Program and ADOS-2 Training Video Program Upgrade were previously offered as DVD training packages. The online self-study programs described here are identical in content to the previous DVD training packages and are changed in delivery format only.
    • ADOS-2 Training Video Program (LMS-605):
      • Covers all five modules of the ADOS-2
      • Designed for professionals who are new to the ADOS-2
      • Online videos featuring case examples for all ADOS-2 modules (with a total running time of about 14 hours). The case examples for Modules 1 through 4 are identical to those in the original ADOS DVD training package (since these modules retain basic ADOS activities). The case examples for the Toddler Module are new.
      • Digital support materials for use with the online videos, including Training Videos Guidebook and Training Protocol Booklets
    • ADOS-2 Training Video Program Upgrade (LMS-606):
      • Covers only the Toddler Module
      • Designed for professionals who have already completed training in Modules 1-4 (via live clinical workshops or the original ADOS DVD training package)
      • Online videos featuring case examples for the Toddler Module (with a total running time of about 5 hours)
      • Digital support materials for use with the online videos, including Training Videos Guidebook and Training Protocol Booklets (Note: The portion of the Guidebook covering Modules 1 through 4 can be used only if you have access to the videos from the original ADOS DVD Training Package [W-365DVD]; see next bullet for additional information.)
      • This Upgrade does not include videos for Modules 1 through 4. It must be combined with the ADOS DVD Training Package (W-365DVD) to provide five-module training. It can also be used on its own to provide the training necessary for upgrading skills for use of the Toddler Module.

        If you have videos for Modules 1 through 4 other than the ones from the ADOS DVD Training Package (for example, videos that you may have received by attending an ADOS workshop), those videos are not compatible with this training upgrade package. For five-module video training without access to the original ADOS training videos (W-365DVD), you will need to purchase LMS-605. If you have ADOS training videos but you are unsure whether they will be compatible with this training upgrade package, please contact WPS for clarification.

     

    The ADOS-2 Training Video Program (LMS-605) and the ADOS-2 Training Video Program Upgrade (LMS-606) are available online on the WPS Learning Management System (WPS LMS).

    • To purchase these materials (and the associated continuing education [CE] materials), simply add them to your cart and complete your purchase. You will receive a follow-up email from WPS with information on how to access the materials on the WPS LMS.
    • For additional CE-related information and products, visit our CE page and CE FAQ page

    Have a question about the ADOS-2? Visit the ADOS-2 FAQ page for more information.

    Case Examples

    Chapters 3 and 7 of the ADOS-2 Manual present case examples for using Modules 1 through 4 and the Toddler Module. The case examples include a variety of completed ADOS-2 protocols/algorithms and examples of how to include ADOS-2 results in written reports. Cases range from a toddler exhibiting delays in physical development and social communication to an adult experiencing academic and social difficulties in college. Below is an excerpt from the case example for Module 2.

    Module 2: “Harry”

    Harry is a 6-year-old boy who received a diagnosis of ASD from a statewide early intervention project when he was 2 years old. Harry and his family were recruited to participate in a genetics study of ASD. As part of the study protocol, Harry’s family participated in a research evaluation to confirm Harry’s diagnosis of ASD. Harry’s parents completed a parent interview and several questionnaires. Harry was administered a cognitive test (Differential Ability Scales, Second Edition [DAS-2; Elliot, 2007]) and the ADOS-2.

    On the DAS-2, Harry received a Verbal Cluster score of 70 and a Nonverbal Cluster score of 90, indicating Borderline verbal abilities and Average nonverbal abilities. He was observed to use primarily phrase speech. Although Harry often used sentences that included several words, such as “Where are you going, Daddy?” or “I don’t want to go to school,” he did not use complex sentences that included multiple clauses (e.g., “I don’t want to go to school tomorrow because I am too tired”). Module 2 was selected as the appropriate module based on Harry’s expressive language level.

    Harry’s mother was present for the administration of Module 2 while Harry’s father met separately with another clinician to complete the parent interview portion of the research evaluation. A description of Harry’s social and communicative behavior during the ADOS-2 is provided in the excerpt from his evaluation report, presented next.

    Results

    The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Module 2 was administered to Harry for diagnostic purposes as part of a research protocol for a study of the genetics of autism. The ADOS-2 is a semi-structured, standardized assessment instrument that includes many play-based activities designed to obtain information in the areas of communication, reciprocal social interactions, and restricted and repetitive behaviors associated with a diagnosis of ASD. Module 2 of the ADOS-2 is designed for children with phrase speech whose speech is not yet “fluent” (that is, who are not yet consistently combining two relatively complex ideas in sentences to talk about objects or events that are not present). Module 2 includes activities such as a construction task, interactive play with a family of dolls, a demonstration task, looking at a book and pictures, a pretend birthday party, bubbles, and a snack.

    Harry was excited to transition into the more play-based tasks of the ADOS-2 from the cognitive tests that were administered first. He immediately began exploring the various toys that were set out for him. Harry’s language during the ADOS-2 consisted primarily of short phrases. He said things like, “It’s a cat,” as he was pointing to a picture of a cat on the music box, and “I like more,” and “I like two,” when he was requesting things. Harry sometimes echoed things that other people said, such as “Ooh, nice!” or “Alright.” At times, it was quite easy to understand what Harry was saying, but at other times his articulation made it difficult to understand him. He also occasionally mixed up his pronouns, such as saying, “You do it,” to mean that he wanted to do it. Harry had difficulty participating in conversational exchanges with the examiner. Although he was able to answer simple questions about familiar topics (e.g., How old are you? Do you have any pets?), he did not elaborate on his brief answers or ask questions of the examiner when provided opportunities to do so. This made it difficult to build a conversation with Harry.

    Harry sometimes integrated his verbal communication with other modes of nonverbal communication, such as looking at the examiner, smiling, and saying, “Wow,” when he saw something he liked. At other times, he did not use eye contact when talking to people or interacting with them. Harry used a few gestures, such as pretending to brush his teeth when asked to teach this activity to the examiner and blowing a kiss to a baby doll when his mother prompted him to do so. He did not spontaneously use gestures at other times when communicating with the examiner or his mother. 

    In terms of Harry’s social reciprocity during the ADOS-2, he was sometimes quite interested in interacting with the examiner or his mother. He made a variety of overtures to ask for things and occasionally to express interest or draw attention to something that he was enjoying. Harry had a tendency to be repetitive when initiating interactions with other people, however, such as by saying the same phrase in the same way (e.g., saying “You do it, mommy?” with an exaggerated sing-song intonation to ask for permission). Harry also exhibited a strong interest in University of Michigan football, and he insisted on bringing up things about the football team, even when it was clear that the examiner was trying to change the subject. 

    While Harry was often responsive to the examiner’s attempts to talk to him or play with him, he showed less interest in social interaction when he was involved in repetitive play activities. At one point, Harry became very interested in putting small objects into a teapot, then dumping them out and starting over again. When the examiner tried to join Harry and put something into the teapot, he stomped and yelled, “No!” and took it out. On another occasion, Harry spent several minutes putting blocks into a box repetitively. He became quite distressed and frustrated when the examiner tried to interrupt him; he flapped his hands while protesting loudly. 

    Harry exhibited some imaginative play during the ADOS-2. He enjoyed the “Birthday Party” and spontaneously pretended to feed cake to the baby doll. He also rocked the baby doll in a blanket and hugged her as he pretended to put her to bed. Harry had more difficulty playing creatively with the family of dolls. He became so engrossed in playing repetitively with the teapot and the small objects that the repetitive play may have prevented him from using the objects more imaginatively.

    Summary and Recommendations

    Harry’s Overall Total score on the ADOS-2 Module 2 algorithm for children aged 5 years or older was consistent with an ADOS-2 Classification of autism. His ADOS-2 Comparison Score further indicated that, on the ADOS-2, he displayed a high level of autism spectrum–related symptoms as compared with children who have ASD and are of the same chronological age and language level. For the genetics research project protocol, the diagnostic classification of the participants was based on the results of the ADI-R, the ADOS-2, and the clinical impression of the principal investigator (a developmental pediatrician experienced in ASD assessment and diagnosis). Harry’s scores on the ADI-R met cutoffs for autism as well. The senior research clinician reviewed Harry’s charts (including the results of cognitive testing), read the results of the ADI-R, watched a video of the ADOS-2 Module 2 administration, and met with the clinicians who conducted the parent interview and child assessment. Based on the available information, the clinician gave Harry an overall diagnosis of autism and assigned him to the ASD (as opposed to the non-ASD) diagnostic group in the genetics research project. Behavioral observations from the ADOS-2 were used to identify specific intervention targets for Harry’s speech therapy program, such as responding to others’ comments to improve conversational skills. The ADOS-2 was also important in highlighting that Harry’s interests were quite restricted, leading to the goal of increasing his variety of play behaviors.

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